Nimodipine
CAS No. : 66085-59-4
(Synonyms: BAY-e 9736)
| Size | Price | Stock |
|---|---|---|
| 100mg | $40 | In-stock |
| 500mg | $80 | In-stock |
| 1g | $110 | In-stock |
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| Cat. No. : | HY-B0265 |
| M.Wt: | 418.44 |
| Formula: | C21H26N2O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders[1].
IC50 & Target: dihydropyridine calcium[1]
In Vitro: Nimodipine (1.5~150 μg/ml; 15 minutes; B16a and W256 cells) results in a dose-dependent inhibition of B16a and W256 tumor-cell-induced platelet aggregation. Nimodipine is also inhibitory in a homologous system[3].
In Vivo: Nimodipine (0.2 µg/µl, intrathecal administration) prevents subarachnoid hemorrhage-associated cerebral vasospasm by prophylactic continuous intrathecal administration[2].
Nimodipine(0.1~80 mg/kg; p.o.) results in a significant dose-dependent inhibition of spontaneous metastasis[3].
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