LL-Z1640-4


CAS No. : 66018-41-5

66018-41-5
Price and Availability of CAS No. : 66018-41-5
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Cat. No. : HY-120349
M.Wt: 364.39
Formula: C19H24O7
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 66018-41-5 :

LL-Z1640-4 is a potent p38/JNK signaling inhibitor. LL-Z1640-4 significantly diminishes p38 and JNK activation in HCC cells transfected with MLK4 siRNA. LL-Z1640-4 markedly attenuates ROS production induced by MLK4 knockdown. LL-Z1640-4 significantly reduces the apoptotic cells in HCC cells transfected with siMLK4[1][2]. In Vitro: LL-Z1640-4 markedly restores the number of cells in migration and invasion decreased by siMLK4, and significantly up-regulates expression of MMP2 and Vimentin[2].

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