Glucosamine (hydrochloride)


CAS No. : 66-84-2

(Synonyms: D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride)

66-84-2
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Cat. No. : HY-N0733
M.Wt: 215.63
Formula: C6H14ClNO5
Purity: >98 %
Solubility: H2O : 50 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic)
Introduction of 66-84-2 :

Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes[1]. In Vitro: Glucosamine hydrochloride (D-Glucosamine hydrochloride) exhibits dose-dependent DPPH antioxidant activity[2].
Glucosamine hydrochloride treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins[3].
Glucosamine hydrochloride significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells[4].

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