Methyl methanesulfonate


CAS No. : 66-27-3

66-27-3
Price and Availability of CAS No. : 66-27-3
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Cat. No. : HY-W004702
M.Wt: 110.13
Formula: C2H6O3S
Purity: >98 %
Solubility: H2O : ≥ 100 mg/mL;DMSO : 100 mg/mL (ultrasonic)
Introduction of 66-27-3 :

Methyl methanesulfonate is an alkylating agent which transfers methyl groups, and induces DNA damage. Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1][2]. In Vitro:Methyl methanesulfonate (50-800 μM; 24 h) upregulates the generation of phosphorylated p53, RIPK and ROS, induces necroptosis in cell A549[1].
In Vivo:Methyl methanesulfonate (120 mg/kg, ip, single dose) induces DNA damage in mouse models[2].

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