Uracil
CAS No. : 66-22-8
| Size | Price | Stock |
|---|---|---|
| 100g | $15 | In-stock |
| 500g | $33 | In-stock |
| 1000g | $64 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-I0960 |
| M.Wt: | 112.09 |
| Formula: | C4H4N2O2 |
| Purity: | >98 % |
| Solubility: | H2O : 2.5 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : ≥ 25 mg/mL |
Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins[1][2][3][4][5].
In Vitro: Uracil (2500μM) mainly phosphorylates 5-FU (2.5-250 μM) with slightly degradation in Yoshida sarcoma cells, whereas in liver slices, degradation of 5- FU is greater than its phosphorylation[4].
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