Punicalin
CAS No. : 65995-64-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $55 | In-stock |
| 5mg | $150 | In-stock |
| 10mg | $250 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-N0639 |
| M.Wt: | 782.53 |
| Formula: | C34H22O22 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic) |
Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity[1][2][3][4][5][6][7].
In Vitro:Punicalin (0-100 μM, 24 h) improves LPS/ ATP-induced pyroptosis in mouse mononuclear macrophage J774A by inhibiting ROS/NLRP3 pathway<[3].
Punicalin (10, 20 μM, 24 h) alleviates OGD/R-induced cell damage through TGF-β-mediated neuroblastoma SH-SY5Y oxidative stress and cell cycle[4].
In Vivo:Punicalin (5 mg/kg, subcutaneous injection) has an obvious anti-inflammatory effect on carrageenan (HY-125474)-induced metatarsal edema in rats[1].
Punicalin (10 mg/kg, intraperitoneal injection) alleviates LPS (HY-D1056)-induced acute lung injury in mice by inhibiting the production of inflammatory cytokines and MAPK/ NF-κB signaling[5].
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