Metformin (Standard)
CAS No. : 657-24-9
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| Cat. No. : | HY-B0627R |
| M.Wt: | 129.17 |
| Formula: | C4H11N5 |
| Purity: | >98 % |
| Solubility: |
Metformin (Standard) is the analytical standard of Metformin (HY-B0627). This product is intended for research and analytical applications. Metformin (1,1-Dimethylbiguanide) inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, metformin regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1][2][3][4][5][6][7].
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