Avizafone


CAS No. : 65617-86-9

(Synonyms: Pro-diazepam)

65617-86-9
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Cat. No. : HY-123193
M.Wt: 430.93
Formula: C22H27ClN4O3
Purity: >98 %
Solubility:
Introduction of 65617-86-9 :

Avizafone (Pro-diazepam), a pro-drug of Diazepam, is an anticonvulsant agent. Avizafone can be used as an antidote of nerve agent poisoning. In vivo, Avizafone is rapidly hydrolyzed by aminopeptidase to produce lysine and diazepam. Avizafone has research areas including neurological disease, such as epilepsy[1][2][3]. In Vivo:Avizafone (3.5 mg/kg; i.m.; single dose) prevents seizures, reduces clinical signs, eliminates 24-hour mortality, and mitigates brain lesions in Charles River guinea pigs (soman poisoned) (with a 24-hour mortality rate of 0%)[2].

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