4'-Demethylepipodophyllotoxin
CAS No. : 6559-91-7
(Synonyms: 4'-O-demethylepipodophyllotoxin; 4'-DMEP)
| Size | Price | Stock |
|---|---|---|
| 50mg | $5 | In-stock |
| 100mg | $10 | In-stock |
| 1g | $19 | In-stock |
| 5g | $57 | In-stock |
| 25g | $209 | In-stock |
| 100g | $659 | In-stock |
| 200 g | Get quote | |
| 500 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-17435 |
| M.Wt: | 400.38 |
| Formula: | C21H20O8 |
| Purity: | >98 % |
| Solubility: | DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 60°C) |
4'-Demethylepipodophyllotoxin (4'-DMEP) is an intermediate compound that inhibits microtubule assembly.
In Vitro:4'-Demethylepipodophyllotoxin decreases the XooFtsZ'GTPase activity, and shows bacteriostatic effect (EC50 = 38.7 μg/mL) against Xanthomonas oryzae pv. oryzae (Xoo)[3].
4'-Demethylepipodophyllotoxin shows cytotoxicity activity against tumor cells, with EC50 of 0.31, 0.32, 0.37, 0.43 μM for HL-60, K-562, HepG2, KB cells[1].
In Vivo:4'-Demethylepipodophyllotoxin (1 µg/mL, 200 µL, topical application, 24 weeks) reduces the tumor incidence, tumor volume, and the conversion efficiency of papillomas to squamous cell carcinomas in DMBA/TPA-induced mouse skin carcinogenesis model[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- 4'-Demethylepipodophyllotoxin
- Cat. No.:
- HY-17435
- Quantity:
Your information is safe with us.