D-Glucuronic acid
CAS No. : 6556-12-3
| Size | Price | Stock |
|---|---|---|
| 5g | $19 | In-stock |
| 25g | $41 | In-stock |
| 100g | $163 | In-stock |
| 500g | $794 | In-stock |
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| Cat. No. : | HY-N6612 |
| M.Wt: | 194.14 |
| Formula: | C6H10O7 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers, and its derivatives also possess anti-tumor activity[1][2][3][4][5][6]. In Vitro:D-Glucuronic acid (0.05 mM, 22 h) can promote early embryonic development of pig oocytes[3]. A high concentration of D-Glucuronic acid (7 mM, 6 h) significantly inhibits the aggregation factor (AF)-mediated aggregation of GEODIA cells[4][5]. In Vivo:D-Glucuronic acid (0.32 μg, i.t., single dose) can induce tactile allodynia in Sprague-Dawley rats[6].
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