| Size | Price | Stock |
|---|---|---|
| 25g | $13 | In-stock |
| 100g | $27 | In-stock |
| 250g | $30 | In-stock |
| 500g | $33 | In-stock |
| 1000g | $63 | In-stock |
| > 2 kg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-B1469 |
| M.Wt: | 146.14 |
| Formula: | C6H10O4 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 100 mg/mL;DMSO : ≥ 100 mg/mL |
Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic[1][2].
In Vivo: Isosorbide (5 mg/kg; a single p.o.) significantly increases the urine volume of rats within 2 hours which lasts through the 8 hour experimental period[3].
Isosorbide (5 mg/kg; a single p.o. 30 min prior to gallium injection) significantly reduces the urinary concentrations of both gallium and calcium in rats[3].
Isosorbide (5 mg/kg; p.o. 30 min prior to gallium injection for 6 d) results in the formation of fewer renal precipitates and histopathologic changes than in the nondiuresed animals[3].
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