Bometolol Hydrochloride
CAS No. : 65023-16-7
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| Cat. No. : | HY-U00386 |
| M.Wt: | 508.99 |
| Formula: | C25H33ClN2O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease. IC50 & Target: Beta-adrenergic receptor[1] In Vivo: Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats[1].
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