Ethacrynic acid (sodium)
CAS No. : 6500-81-8
(Synonyms: Etacrynic acid (sodium); Sodium etacrynate)
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| Cat. No. : | HY-B1640A |
| M.Wt: | 325.12 |
| Formula: | C13H11Cl2NaO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice[1][2][3][4].
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