4-Aminosalicylic acid
CAS No. : 65-49-6
| Size | Price | Stock |
|---|---|---|
| 25g | $12 | In-stock |
| 100g | $19 | In-stock |
| 500g | $64 | In-stock |
| 1000g | $106 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-I0447 |
| M.Wt: | 153.14 |
| Formula: | C7H7NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
4-Aminosalicylic acid is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. 4-Aminosalicylic acid exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). 4-Aminosalicylic acid is orally active[1][1][3].
In Vitro:4-Aminosalicylic acid is incorporated into the folate pathway via dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate the hydroxydihydrofolate antimetabolite, which in turn inhibits DHFR enzyme activity[1].
4-Aminosalicylic acid inhibits M. tuberculosis H37Rv growth with MIC value of 0.4 μM[1].
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