Yohimbine (Hydrochloride) (Standard)


CAS No. : 65-19-0

65-19-0
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Cat. No. : HY-N0127R
M.Wt: 390.90
Formula: C21H27ClN2O3
Purity: >98 %
Solubility:
Introduction of 65-19-0 :

Yohimbine Hydrochloride Standard is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis. In Vivo: Yohimbine Hydrochloride Standard (0.2 mg/kg, i.p.) was administered to rats 1h before the stress session daily for 14 consecutive days and its effect was assessed. Results of this section revealed that, immersion of rats in cold water significantly decreased sexual arousal and motivation as indicated by increased latencies and intervals. Decreased copulatory activity was confirmed by decreased testosterone, luteinizing hormone (LH) and follicle-stimulating-hormone (FSH) levels as well as decreased cholesterol content in rat testes. Treatment with yohimbine significantly increased the sexual arousal and potency and corrected the effects induced by stress on the mating behavior of male rats[1].

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