MCHR1 antagonist 6
CAS No. : 645399-82-2
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| Cat. No. : | HY-119015 |
| M.Wt: | 341.47 |
| Formula: | C19H23N3OS |
| Purity: | >98 % |
| Solubility: |
MCHR1 antagonist 6 is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. MCHR1 antagonist 6 interacts with receptor residue D123 via its central basic group, and forms hydrogen bonds with receptor residue Q127 via its 2-amino-quinoline portion. MCHR1 antagonist 6 can be used for the research of obesity[1]. In Vitro:MCHR1 antagonist 6 (Compound 7) potently inhibits 125I-MCH binding to h-MCH-R1 expressed in HEK293 cells with an IC50 of 15 nM[1].
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