Oxprenolol
CAS No. : 6452-71-7
(Synonyms: Ba 39089 (free base))
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| Cat. No. : | HY-B1486A |
| M.Wt: | 265.35 |
| Formula: | C15H23NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].
In Vitro: Oxprenolol is lipophilic[3].
Oxprenolol shows permeability rate constant of 1.54 ± 1.54×10-3 cm/h across abdominal human skin[3].
In Vivo: Oxprenolol (200 mg/kg/day; p.o.; daily for 3 weeks) produces effective beta-blockade together with peak plasma drug levels within the normal clinical range[2].
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