Guanethidine (sulfate)
CAS No. : 645-43-2
(Synonyms: Guanethidine monosulfate)
| Size | Price | Stock |
|---|---|---|
| 100mg | $60 | In-stock |
| 500mg | $132 | In-stock |
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| Cat. No. : | HY-B0800 |
| M.Wt: | 296.39 |
| Formula: | C10H24N4O4S |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier[1][2]. In Vivo:Guanethidine sulfate (5-40 mg/kg; intraperitoneal injection; daily; for 4-28 days; male Wistar rats) treatment for 28 days by 40 mg/kg results in an incomplete sympathectomy accompanied by a partially irreversible hypersensitivity to noradrenaline, whereas 5 mg/kg does not induce histological or permanent haemodynamic changes[2].
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