2-Hydroxychalcone
CAS No. : 644-78-0
| Size | Price | Stock |
|---|---|---|
| 500mg | $25 | In-stock |
| 1g | $40 | In-stock |
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| Cat. No. : | HY-119931 |
| M.Wt: | 224.25 |
| Formula: | C15H12O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3].
In Vitro: 2-Hydroxychalcone inhibits invasion of triple negative breast cancer cells[1].
2-hydroxychalcone inhibits the adhesion of peripheral neutrophils to the endothelial cell monolayers by inhibiting the expression of ICAM-1, VCAM-1, and E-selectin in a concentration-dependent manner[2].
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