| Size | Price | Stock |
|---|---|---|
| 5mg | $46 | In-stock |
| 10mg | $72 | In-stock |
| 50mg | $288 | In-stock |
| 100mg | $468 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-B1324 |
| M.Wt: | 492.14 |
| Formula: | C18H14Cl4N4O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest[1][2][3].
IC50 & Target: MIC90: 0.25 μg/mL (T. tonsurans), 0.5 μg/mL (T. rubrum)[1]
In Vitro: Oxiconazole (24 h; 0-40 μM) inhibits CRC cell growth[3].
Oxiconazole has antifungal activity against Candida, Aspergillus and Trichophyton[1].
Antifungal Activities of Oxiconazole[1].
| Candidaalbicans | Candidaglabrata | Candidaparapsilosis | Aspergillusfumigatus | Aspergillusflavus | Trichophytonmentagrophytes | Trichophytonrubrum | |
| Oxiconazole | 0.03 μg/mL | 0.01 μg/mL | 0.008 μg/mL | 2 μg/mL | 2 μg/mL | 2 μg/mL | 2 μg/mL |
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