Valopicitabine (dihydrochloride)
CAS No. : 640725-71-9
(Synonyms: NM283 (dihydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $430 | In-stock |
| 10mg | $680 | In-stock |
| 25mg | $1300 | In-stock |
| 50mg | $2050 | In-stock |
| 100mg | $3200 | In-stock |
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| Cat. No. : | HY-108060A |
| M.Wt: | 429.30 |
| Formula: | C15H26Cl2N4O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
Valopicitabine (NM283) dihydrochloride is a nucleoside analog and the orally bioavailable proagent of the potent anti-HCV agent 2'-C-methylcytidine (NM107). NM107competitively inhibits NS5B polymerase, causing chain termination[1][2]. In Vivo: Valopicitabine (NM283) (100 mg/kg; oral administration; Sprague-Dawley Rats) dihydrochloride shows the Cmax, AUC, t1/2, and tmax were 3.624 μg/mL, 8.95 μg h/mL, 0.64 hours and 1 hour, respectively[2].
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