Ro 04-5595 (hydrochloride)


CAS No. : 64047-73-0

64047-73-0
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Cat. No. : HY-107696
M.Wt: 368.30
Formula: C19H23Cl2NO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 64047-73-0 :

Ro 04-5595 hydrochloride is a GluN2B-selective NMDA receptor antagonist (Ki: 31 nM)[1]. In Vivo:Ro 04-5595 hydrochloride (5-20 mg/kg, i.p.) inhibits MA-induced locomotor stimulation in mice[2].
Ro 04-5595 hydrochloride (10 mg/kg, i.p., for 6 days) reduced AMPA to NMDA ratio in Cocaine self-administering rats[3].

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