Ethacridine (lactate monohydrate)
CAS No. : 6402-23-9
(Synonyms: Acrinol (monohydrate))
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| Cat. No. : | HY-B0889 |
| M.Wt: | 361.39 |
| Formula: | C18H23N3O5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : 2 mg/mL (ultrasonic) |
Ethacridine lactate (Acrinol) monohydrate is a widely used antiseptic and abortifacient. Ethacridine lactate monohydrate is effective against Staphylococcus aureus and other gram-positive cocci. Ethacridine lactate monohydrate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1][2][3]. IC50 & Target: poly(ADP-ribose) glycohydrolase (PARG)[2] In Vitro: Acrinol is effective against S. aureus including MRSA, with the MICs ranging from 100-200 μg/mL. The MIC of Acrinol for Eschericia coli is 200-800 μg/mL, and it is over 1,600 μg/mL for Proteus vulgaris and Proteus mirabilis[3]. In Vivo: Ethacridine lactate can be used for termination of pregnancy[1].
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