Chlortetracycline (hydrochloride)
CAS No. : 64-72-2
(Synonyms: 7-Chlorotetracycline (hydrochloride))
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| Cat. No. : | HY-B1327 |
| M.Wt: | 515.34 |
| Formula: | C22H24Cl2N2O8 |
| Purity: | >98 % |
| Solubility: | H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes[1][2][3][4].
In Vitro: Chlortetracycline hydrochloride (10, 50, 100, 200 mg/L, 18 days) inhibits methane (a main component of biogas) production and is degradated and metabolized by anaerobic digestion (AD) at high concentrations and incubation temperatures[3].
In Vivo: Chlortetracycline hydrochloride (50 mg/kg, p.o., administration for 42 consecutive days) significantly increases the IgM antibody levels and decreases the IgA antibody levels in serum of mice[4].
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