Artemisinin
CAS No. : 63968-64-9
(Synonyms: Qinghaosu; NSC 369397)
| Size | Price | Stock |
|---|---|---|
| 100mg | $25 | In-stock |
| 200mg | $43 | In-stock |
| 500mg | $84 | In-stock |
| 1g | $145 | In-stock |
| 5g | $260 | In-stock |
| 10g | $350 | In-stock |
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| Cat. No. : | HY-B0094 |
| M.Wt: | 282.33 |
| Formula: | C15H22O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic) |
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].
In Vitro: Artemisinin (Qinghaosu) (25 or 50 μM; 24 hours) concentration-dependently suppresses Aβ25-35 induced cytotoxicity in PC12 cells[1].
Artemisinin (1-100 μM; 24 hours) selectively inhibits cancer cell growth in a dose-dependent manner with IC50 values of 31.30 ± 0.73 μM in UMRC-2 cells and 23.97 ± 0.92 CAKI-2 cells[2].
Artemisinin (25, 50 μM; 24 hours) suppresses the phosphorylation of AKT in UMRC-2 and CAKI-2 cells in a dose-dependent manner[2].
In Vivo: Artemisinin (gavage; 20 mg/kg/day; for two weeks) suppresses UMRC-2 xenograft tumor growth[2].
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