Meclofenamic acid (sodium)


CAS No. : 6385-02-0

(Synonyms: Meclofenamate (sodium))

6385-02-0
Price and Availability of CAS No. : 6385-02-0
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50mg $55 In-stock
100mg $99 In-stock
200mg $165 In-stock
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Cat. No. : HY-B1320
M.Wt: 318.13
Formula: C14H10Cl2NNaO2
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic)
Introduction of 6385-02-0 :

Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities[1][2][3]. In Vitro: Meclofenamic acid sodium (10, 100, 200 mM, 4 days) inhibits the proliferation and migration of haSMCs[1].
Meclofenamic acid sodium (4, 6 μM, 48 h) combines with gefitinib-induced caspase-related apoptosis of resistant NSCLC cells[2].
In Vivo: Meclofenamic acid sodium (10 mg/kg/day, intraperitoneally injected for 20 days) shows antitumor activity in mouse prostate tumor model[2].

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