Ocrelizumab
CAS No. : 637334-45-3
(Synonyms: 2H7; PRO70769; RG1594)
| Size | Price | Stock |
|---|---|---|
| 1mg | $300 | In-stock |
| 5mg | $780 | In-stock |
| 10mg | $1250 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-P9960 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O |
Ocrelizumab (Ocrevus) is a humanized anti-CD20 monoclonal antibody. Ocrelizumab can induce B cell depletion and inhibit multiple sclerosis lesions in mice through antibody dependent cytotoxicity (ADCC)[1][2]. IC50 & Target:CD20/MS4A1 In Vivo: Ocrelizumab (7.5 mg/kg; once daily; 18 days; s.c. or i.v.) inhibits lesions in multiple sclerosis mice by inducing B cell exhaustion through antibody dependent cytotoxicity (ADCC)[1]. Ocrelizumab (50 μg; repeat administration on days 7, 14, and 21; i.v.) can reduce B and T cells in the blood, lymph nodes, and spleen of C57BL/6 mice[2].
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