Cicloprolol (hydrochloride)
CAS No. : 63686-79-3
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| Cat. No. : | HY-U00066 |
| M.Wt: | 359.89 |
| Formula: | C18H30ClNO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Cicloprolol is a partial β 1-adrenoceptor agonist . IC50 & Target: Adrenoceptor[1] In Vitro: Cicloprolol is a partial β1-adrenoceptor agonist considered for the treatment of patients with coronary artery disease and impaired left ventricular function[1]. The new β-adrenoceptor partial agonist Cicloprolol acts as a β-agonist at normal levels and as a β-antagonist at high levels of adrenergic discharge. Treatment with Cicloprolol should protect the heart against excessive stimulation, while providing a baseline level of sympathetic drive. Cicloprolol has a weak β1-agonistic effect at normal levels of adrenergic discharge and acts as an antagonist at high levels of discharge[2].
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