Indobufen
CAS No. : 63610-08-2
(Synonyms: Ibustrin)
| Size | Price | Stock |
|---|---|---|
| 100mg | $25 | In-stock |
| 250mg | $53 | In-stock |
| 500mg | $80 | In-stock |
| 1g | $120 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-18763 |
| M.Wt: | 295.33 |
| Formula: | C18H17NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes[1]. In Vitro: Indobufen does not affect both Cox-1 and Cox-2 protein, whereas Indobufen reduces TxB2 levels. Indobufen inhibits TxA2 but not PGE2 synthesis in LPS-stimulated monocytes. Indobufen reduces the extent of ERK1/2 phosphorylation, whereas the levels of phosphorylated p38 are unaltered[1].
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