Pyridine-3-sulfonic acid


CAS No. : 636-73-7

(Synonyms: Pyridine-3-sulphonic acid)

636-73-7
Price and Availability of CAS No. : 636-73-7
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Cat. No. : HY-W015467
M.Wt: 159.17
Formula: C5H5NO3S
Purity: >98 %
Solubility:
Introduction of 636-73-7 :

Pyridine-3-sulfonic acid (Pyridine-3-sulphonic acid) is an orally active structural analog of Nicotine acid (HY-B0143). Pyridine-3-sulfonic acid significantly reduces hepatic cholesterol synthesis in rats but lacks cholesterol-lowering activity. Pyridine-3-sulfonic acid does not interfere with the metabolism of Nicotine acid[1][2]. In Vivo:Pyridine-3-sulfonic acid (1%, 1 g/100 g daily diet, p.o. with food, for 21 days) significantly reduces liver cholesterol synthesis in rats[1].
Pyridine-3-sulfonic acid (0.5-2 g, p.o. with food) does not interfere with the binding or metabolism of nicotinamide to coenzyme I/II in normal dogs or dogs deficient in Niacin[2].

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