Bilirubin
CAS No. : 635-65-4
| Size | Price | Stock |
|---|---|---|
| 50mg | $50 | In-stock |
| 100mg | $80 | In-stock |
| 250mg | $160 | In-stock |
| 500mg | $260 | In-stock |
| 1g | $420 | In-stock |
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| Cat. No. : | HY-N0323 |
| M.Wt: | 584.66 |
| Formula: | C33H36N4O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C);0.1 M NaOH : < 1 mg/mL (ultrasonic;warming;adjust pH to 9 with H2O;heat to 60°C) |
Bilirubin is a yellow breakdown product of heme catabolism[1]. Bilirubin exhibits antioxidant and antimutagenic effects[2]. In Vitro:Unconjugated Bilirubin inhibits the cleavage of F485-rVWF73-H, D633-rVWF73-H, and GST-rVWF71-11K by ADAMTS13 in a concentration-dependent manner with a half-maximal inhibitory concentration (IC50) of ~13 μM, ~70 μM, and ~17 μM, respectively. Unconjugated Bilirubin also dose-dependently inhibits the cleavage of multimeric VWF by ADAMTS13 under denaturing conditions[1]. Bilirubin exhibits antioxidant and antimutagenic effects in vitro[2].
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