2-Chloroisonicotinic acid


CAS No. : 6313-54-8

6313-54-8
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Cat. No. : HY-65003
M.Wt: 157.56
Formula: C6H4ClNO2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 6313-54-8 :

2-Chloroisonicotinic acid is a compound with anti-inflammatory properties that serves as an active intermediate. 2-Chloroisonicotinic acid can be used in inflammation-related research[1]. In Vitro:2-Chloroisonicotinic acid can be obtained via purification after a catalytic reaction catalyzed by nitrilase-CLEAs[1]. In Vivo:2-Chloroisonicotinic acid (50 mg/kg, i.p., single administration; administered 1 h prior to carrageenan-induced modeling) exhibits anti-inflammatory activity in outbred white rats with carrageenan-induced paw edema, with edema growth inhibition rates of 61.2% and 59.4% at 3 h and 5 h post-administration, respectively[1].

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