β-Boswellic acid
CAS No. : 631-69-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $290 | In-stock |
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| Cat. No. : | HY-N2513 |
| M.Wt: | 456.70 |
| Formula: | C30H48O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
β-Boswellic acid is isolated from the gum resin of Boswellia serrata with anticancer, antioxidant activity, anti-inflammatory activity and anti-arthritic pain.β-Boswellic acid is an orally active nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells with IC50 values ranging from 0.6 to 7.1 μM. β-Boswellic acid is promising for research of diabetes, inflammatory and arthritic diseases[1][2][3][4].
In Vitro:β-Boswellic acid (0-34 μM, 120 min) inhibits DNA, RNA and protein synthesis of HL-60 cells in a dose-dependent manner[2].
In Vivo:β-Boswellic acid (1-20 mg/kg, p.o., daily for 21 days) lowers the blood glucose level, reverses Streptozotocin (STZ) (HY-13753)-mediated bodyweight reduction and reduces the levels of TC, TGs, LDL cholesterol and the serum SGPT, SGOT, ALP and serum creatinine in STZ-induced diabetic rats[4].
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