Terazosin (hydrochloride)


CAS No. : 63074-08-8

63074-08-8
Price and Availability of CAS No. : 63074-08-8
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Cat. No. : HY-B0371F
M.Wt: 423.89
Formula: C19H26ClN5O4
Purity: >98 %
Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 63074-08-8 :

Terazosin hydrochloride is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment[1][2][3]. IC50 & Target: α1-adrenoceptor[1] In Vitro: Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells[1]. In Vivo: Terazosin can be used to promote stone discharge in treatment of ureteral stones. Terazosin is reportedly safe and effective in treatment of distal ureteral stones, especially stones >5 mm[3].

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