NSC45586 (sodium)


CAS No. : 6300-44-3

6300-44-3
Price and Availability of CAS No. : 6300-44-3
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5mg $125 In-stock
10mg $175 In-stock
25mg $295 In-stock
50mg $440 In-stock
100mg $700 In-stock
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Cat. No. : HY-19820A
M.Wt: 412.38
Formula: C20H17N6NaO3
Purity: >98 %
Solubility: H2O : 5 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 6300-44-3 :

NSC45586 sodium is an inhibitor of pleckstrin homology domain and leucine-rich repeat protein phosphatase (PHLPP). NSC45586 sodium targets the PP2C phosphatase domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons[1]. IC50 & Target:PHLPP1/2, Akt[1]

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