L-Methionine


CAS No. : 63-68-3

63-68-3
Price and Availability of CAS No. : 63-68-3
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Cat. No. : HY-N0326
M.Wt: 149.22
Formula: C5H11NO2S
Purity: >98 %
Solubility: H2O : 10 mg/mL (ultrasonic)
Introduction of 63-68-3 :

L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity[1][2][3]. In Vitro:L-Methionine (5 mg/mL, 7 or 3 days) can inhibit the proliferation of BXPC-3 (mutant p53) and HPAC (wild-type p53) pancreatic cancer cells, interfere with cell cycle, and induce apoptosis of BXPC-3 cells[1].
L-Methionine (0.3-10 mM, 24 h) reduces the formation of free radicals in endothelial cells by inducing heme oxidase-1 and ferritin[2].
In Vivo:L-Methionine (215, 268.8, 322.5, 430 mg/kg, orally, for 14 consecutive days) induces endogenous antioxidant activity by activating the Nrf2-ARE pathway and inhibits ROS-induced oxidative stress in growing rats[3].

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