CAS No. : 63-45-6
(Synonyms: Primaquine (phosphate); Primaquine (bisphosphate))
| Size | Price | Stock |
|---|---|---|
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| 1g | $48 | In-stock |
| 5g | $86 | In-stock |
| 10g | $130 | In-stock |
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| Cat. No. : | HY-12651 |
| M.Wt: | 455.34 |
| Formula: | C15H27N3O9P2 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 250 mg/mL (ultrasonic) |
Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria[1]. In Vitro:Primaquine diphosphate significantly decreases the cell proliferation of live breast cancer cells, and shows no inhibitory effect on the proliferation of MCF-7 (ER+) and MDA-MB-453 (HER2+) cells. Primaquine diphosphate inhibits the growth, migration, and colony formation of breast cancer cells in vitro[3]. In Vivo:Primaquine (5-25 mg/kg; p.o; daily; for 3 days) diphosphate demonstrates no bioluminescence liver signal and no blood stage parasitaemia[2].
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