Primaquine (diphosphate)


CAS No. : 63-45-6

(Synonyms: Primaquine (phosphate); Primaquine (bisphosphate))

63-45-6
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10g $130 In-stock
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Cat. No. : HY-12651
M.Wt: 455.34
Formula: C15H27N3O9P2
Purity: >98 %
Solubility: H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 250 mg/mL (ultrasonic)
Introduction of 63-45-6 :

Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria[1]. In Vitro:Primaquine diphosphate significantly decreases the cell proliferation of live breast cancer cells, and shows no inhibitory effect on the proliferation of MCF-7 (ER+) and MDA-MB-453 (HER2+) cells. Primaquine diphosphate inhibits the growth, migration, and colony formation of breast cancer cells in vitro[3]. In Vivo:Primaquine (5-25 mg/kg; p.o; daily; for 3 days) diphosphate demonstrates no bioluminescence liver signal and no blood stage parasitaemia[2].

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