| Size | Price | Stock |
|---|---|---|
| 1mg | $150 | In-stock |
| 5mg | $370 | In-stock |
| 10mg | $550 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-111588 |
| M.Wt: | 392.49 |
| Formula: | C25H28O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity. Xanthoangelol inhibits monoamine oxidases. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[1][2][3][4].
In Vitro:Xanthoangelol (1 and 5 μM, 24 h) combined with 4-HD suppresses proinflammatory factors, such as NO, TNF-a, and MCP-1 through inhibition of the JNK pathway in the co-culture system of fully differentiated 3T3-L1 adipocytes and RAW264.7 macrophages[1].
Xanthoangelol (1-100 μM, 48 h) reduces the neuroblastoma and leukemia cells survival with cytotoxicity[4].
Xanthoangelol (1-10 μM, 4 h) induces concentration-dependent early apoptosis followed by secondary cell death through activation of caspase-3 in Jurkat cells[4].
In Vivo:Xanthoangelol (0.1% or 0.15% w/w, mixed in a high-fat diet, daily for 14 weeks) suppresses inflammatory mediators in WAT of diet-induced obese mice[1].
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