Meglumine
CAS No. : 6284-40-8
(Synonyms: Methylglucamine; Meglumin; Methylglucamin)
| Size | Price | Stock |
|---|---|---|
| 100g | $20 | In-stock |
| 500g | $52 | In-stock |
| 1000g | $83 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-B0342 |
| M.Wt: | 195.21 |
| Formula: | C7H17NO5 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide[1][2][3].
In Vitro:Meglumine (40 or 80 mM, 24 h; 50 mM, 24 h) dose-dependently reduces the levels of inflammatory factors in THP-1 human myeloid cells and RAW264.7 mouse macrophage cells (Elisa assay)[2].
Meglumine (0-300 mM, 60 min) dose-dependently increases SNARK expression levels in C2C12 mouse myoblasts[4].
In Vivo:Meglumine (25 or 50 mM; 37.5 mM, taken orally dissolved in water) reduces levels of inflammatory factors and inhibits skin cancer tumor growth in rats and mice[2].
Meglumine (18 mM, oral gavage) improves muscle function, limits metabolic syndrome, and reduces diabetic complications in type 2 diabetic mice[4].
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