L-Homocystine


CAS No. : 626-72-2

626-72-2
Price and Availability of CAS No. : 626-72-2
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1g $5 In-stock
5g $14 In-stock
25g $66 In-stock
50g $127 In-stock
100g $240 In-stock
500g $719 In-stock
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Cat. No. : HY-W011690
M.Wt: 268.35
Formula: C8H16N2O4S2
Purity: >98 %
Solubility: DMSO : 1 mg/mL (ultrasonic;adjust pH to 5 with HCl);H2O : 1.67 mg/mL (ultrasonic;warming;adjust pH to 2 with HCl;heat to 60°C)
Introduction of 626-72-2 :

L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms. In Vivo: A single or multiple doses of L-Homocystine administered to mice during organogenesis can aggravate the developmental disturbances caused by a single dose of VPA administered on GD 8. Whereas, VPA lowers significantly plasma FA and vitamin B12 concentrations, it has no direct impact on the homocysteine concentrations. Therefore, it is proposed that high levels of homocysteine disturb the FA, vitamin B12, and possibly methionine metabolism thus providing a favorable situation for VPA to interfere with the development of susceptible embryos[1].

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