TS-021 (free base)
CAS No. : 625110-37-4
(Synonyms: DPP-IV-IN-1)
| Size | Price | Stock |
|---|---|---|
| 5mg | $470 | In-stock |
| 10mg | $760 | In-stock |
| 25mg | $1520 | In-stock |
| 50mg | $1980 | In-stock |
| 100mg | $2780 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-U00346 |
| M.Wt: | 243.28 |
| Formula: | C11H18FN3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM. In Vivo: DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading, and significantly suppresses hyperglycemia at the dose of 0.3 mg/kg in a rat model of obesity and impaired glucose tolerance. The effect is based on its inhibitory effect on plasma DPP-IV activity[1].
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