Methoxyacetic acid


CAS No. : 625-45-6

625-45-6
Price and Availability of CAS No. : 625-45-6
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Cat. No. : HY-Y1009
M.Wt: 90.08
Formula: C3H6O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic)
Introduction of 625-45-6 :

Methoxyacetic acid is a metabolite of ethylene glycol monomethyl ether. When the concentration of methoxyacetic acid reaches a certain level, it can inhibit the respiratory function of hepatic mitochondria and testicular mitochondria. Methoxyacetic acid is somewhat toxic[1][2]. In Vitro:Methoxyacetic acid (>5 mM) inhibits the state 3 succinate oxidation rate and the respiratory control ratio in hepatic mitochondria[1].
Methoxyacetic acid (>3 mM) inhibits the ascorbate/TMPD oxidation rate in testicular mitochondria[1]. In Vivo:Methoxyacetic acid (30-300 mg/kg; oral gavage; 8 times, dosed over 10 days) is somewhat toxic to male Fischer 344 rats[2].

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