Gastrodin


CAS No. : 62499-27-8

(Synonyms: Gastrodine)

62499-27-8
Price and Availability of CAS No. : 62499-27-8
Size Price Stock
25mg $35 In-stock
50mg $56 In-stock
100mg $89 In-stock
500mg $225 In-stock
1g $360 In-stock
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Cat. No. : HY-N0115
M.Wt: 286.28
Formula: C13H18O7
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL;H2O : 100 mg/mL (ultrasonic)
Introduction of 62499-27-8 :

Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia[1][2][3]. In Vitro:Gastrodin treatment reduces the mRNA expression levels of TNF-α and iNOS in the retinas of acute ocular hypertension[1]. In Vivo:Intraperitoneal injection with Gastrodin 10 mg/kg or 50 mg/kg once daily for 15 d significantly inhibits the loss of retinal ganglion cells (RGCs) because of acute ocular hypertension (AOH) damage. 2 wk after AOH, the number of Iba1 positive retinal microglia obviously reduces to 231.3±54.3 cells/mm2 and 201.9±43.1 cells/mm2 in the rats intraperitoneally injected with Gastrodin at 10 mg/kg and 50 mg/kg, respectively[1].

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