Oxyntomodulin (bovine, porcine)
CAS No. : 62340-29-8
(Synonyms: Glucagon-37 (bovine, porcine))
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| 10mg | $750 | In-stock |
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| Cat. No. : | HY-P1144 |
| M.Wt: | 4421.86 |
| Formula: | C192H295N59O60S |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);0.01 M Acetic acid : ≥ 25 mg/mL |
Oxyntomodulin (bovine, porcine), a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1]. In Vitro: Oxyntomodulin (bovine, porcine) is a peptide hormone released from the gut in post-prandial state that activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR) resulting in superior body weight lowering to selective GLP1R agonists. Oxyntomodulin is mainly produced in gut endocrine L-cells by processing of the preproglucagon precursor by prohormone convertase 1/3. Oxyntomodulin is a full agonist in cell lines over expressing the human GLP1R and GCGR-mediated cAMP accumulation although with reduced affinity compared to GLP-1 and glucagon[1].
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