Diethyl fumarate
CAS No. : 623-91-6
| Size | Price | Stock |
|---|---|---|
| 100g | $15 | In-stock |
| 500g | $50 | In-stock |
| 1000g | $90 | In-stock |
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| Cat. No. : | HY-W010056 |
| M.Wt: | 172.18 |
| Formula: | C8H12O4 |
| Purity: | >98 % |
| Solubility: | H2O : 3 mg/mL (ultrasonic);DMSO : 140 mg/mL (ultrasonic) |
Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and reactant in the Diels-Alder reaction. Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin (HY-N0005) hybridize to exert neuroprotective effects[1][2][3][4].
In Vitro:Curcumin-Diethyl fumarate (DEF) hybrids (5 μM) show neuroprotective effects in a C. elegans model of PD[3].
In Vivo:Diethyl fumarate (0.5-50 mM; applied to both sides of the guinea pig earlobes) causes dose-dependent swelling of the ears in guinea pigs[2].
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