Bromotetrandrine
CAS No. : 62067-29-2
(Synonyms: 5-Bromotetrandrine; BrTet; W198)
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| Cat. No. : | HY-121247 |
| M.Wt: | 701.65 |
| Formula: | C38H41BrN2O6 |
| Purity: | >98 % |
| Solubility: |
Bromotetrandrine is a potent inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). Bromotetrandrine shows significant MDR reversal activity in vitro and in vivo, which may be related to the inhibition of P-gp overexpression and the increase in intracellular accumulation of anticancer agents. Bromotetrandrine is a brominated derivative of tetrandrine, which is promising for MDR modulator for tumor assessment[1][2].
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