Diphenmanil (methylsulfate)


CAS No. : 62-97-5

(Synonyms: Diphemanil mesylate)

62-97-5
Price and Availability of CAS No. : 62-97-5
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Cat. No. : HY-16171
M.Wt: 389.51
Formula: C21H27NO4S
Purity: >98 %
Solubility: H2O : 16.67 mg/mL (ultrasonic)
Introduction of 62-97-5 :

Diphemanil methylsulfate is a quaternary ammonium anticholinergic. It binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids as well as saliva and sweat. IC50 value: Target: mAChR Diphemanil Methylsulfate exerts its action by primarily binding the muscarinic M3 receptor. M3 receptors are located in the smooth muscles of the blood vessels, as well as in the lungs. This means they cause vasodilation and bronchoconstriction. They are also in the smooth muscles of the gastrointestinal tract (GIT), which help in increasing intestinal motility and dilating sphincters. The M3 receptors are also located in many glands which help to stimulate secretion in salivary glands and other glands of the body.

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