AZD5904
CAS No. : 618913-30-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $82 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $620 | In-stock |
| 100mg | $950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-111341 |
| M.Wt: | 252.30 |
| Formula: | C10H12N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. IC50 & Target: IC50: 140 nM (human MPO)[1] In Vitro: AZD5904 is a pselective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. In isolated human neutrophils, 1 µM AZD5904 inhibits PMA stimulated HOCl by >90%[1].
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