GS-9667
CAS No. : 618380-90-8
(Synonyms: CVT 3619)
| Size | Price | Stock |
|---|---|---|
| 5mg | $350 | In-stock |
| 10mg | $490 | In-stock |
| 25mg | $790 | In-stock |
| 50mg | $1100 | In-stock |
| 100mg | $1500 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-19842 |
| M.Wt: | 461.51 |
| Formula: | C21H24FN5O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
GS-9667 (CVT 3619), a novel N6-5'-substituted adenosine analog, is a selective, partial agonist of the A1 adenosine receptor (A1AdoR). GS-9667 binds to adipocyte membranes with high (KH=14 nM) and low (KL=5.4 μM) affinities. GS-9667 reduces cyclic AMP content and release of nonesterified fatty acids from epididymal adipocytes with IC50 values of 6 nM and 44 nM, respectively. GS-9667 inhibits lipolysis and has the potential for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA)[1][2].
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