Sipeimine (Standard)
CAS No. : 61825-98-7
(Synonyms: Imperialine (Standard))
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| Cat. No. : | HY-N0696R |
| M.Wt: | 429.64 |
| Formula: | C27H43NO3 |
| Purity: | >98 % |
| Solubility: |
Sipeimine (Standard) is the analytical standard of Sipeimine. Sipeimine (Imperialine) is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65. Sipeimine inhibits PI3K/AKT phosphorylation, blocks NF-κB nuclear translocation and NLRP3 inflammasome activation. Sipeimine exerts anti-inflammatory activities, inhibits pyroptosis and ferroptosis, and protects the extracellular matrix. Sipeimine can reduce cartilage degradation and synovial inflammation in osteoarthritis and improve PM2.5-induced lung injury. Sipeimine is mainly used in the study of anti-inflammatory and degenerative diseases[1][2].
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